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WebFeb 17, 2024 · Introduction. Cornelia de Lange Syndrome (CdLS, OMIM #122470, #300590, #610759, #614701, #300882, # 611192, #608749) is a rare genetic disorder affecting a … WebSep 2, 2024 · Background Cornelia de Lange syndrome (CdLS) is a rare multisystem genetic disorder which is caused by genetic defects involving the Nipped-B-like protein (NIPBL) gene in the majority of clinical cases (60–70%). Currently, there are no specific cures available for CdLS and clinical management is needed for life. Disease models are … epc certificate wigan
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