Gmp synthase glutamine-hydrolysing
WebGMP synthase (glutamine—hydrolysing) and Adenosine triphosphate · See more » Biomolecular structure. Biomolecular structure is the intricate folded, three-dimensional … WebProtein target information for GMP synthase [glutamine-hydrolyzing] ([Haemophilus] ducreyi 35000HP). Find diseases associated with this biological target and compounds …
Gmp synthase glutamine-hydrolysing
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WebNov 15, 2024 · The genes encoding enzymes such as hydrolase, glutamine-hydrolysing GMP synthase, IMP dehydrogenase, and methenyltetrahydrofolate cyclohydrolase FolD were all significantly upregulated. In general, the expression of the glutamine-hydrolysing GMP synthase gene was upregulated 5-fold. Redox-related genes were found to be … WebGene Ontology Term: GMP synthase (glutamine-hydrolyzing) activity. GO ID. GO:0003922. Aspect. Molecular Function. Description. Catalysis of the reaction: ATP + …
WebCatalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate. 1 publication Catalytic activity ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H + + L-glutamate 1 … WebIn enzymology, a GMP synthetase (glutamine-hydrolysing) ( EC 6.3.5.2) is an enzyme that catalyzes the chemical reaction. The 4 substrates of this enzyme are ATP, xanthosine 5' …
WebIt functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (345 aa) … WebGMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] Organism: sao Staphylococcus aureus subsp. aureus NCTC8325. Pathway: sao00230 : Purine metabolism: sao01100 : ... 6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor 6.3.5.2 GMP synthase (glutamine-hydrolysing) SAOUHSC_00375 (guaA) Peptidases and inhibitors …
WebPharmacological inhibition or knockdown of GMPS significantly decreased cell growth in both LNCaP and PC-3 prostate cancer cells. We utilized [15 N-(amide)]glutamine and [U-13 C 5]glutamine metabolomics to dissect the pathways involved and despite similar growth inhibition by GMPS knockdown, we show unique metabolic effects across each cell ...
WebGuanosine monophosphate synthetase, also known as GMPS is an enzyme that converts xanthosine monophosphate to guanosine monophosphate. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide … towed brake systemWeb6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor 6.3.5.2 GMP synthase (glutamine-hydrolysing) SAOUHSC_00375 (guaA) Peptidases and inhibitors … powdersville sc new homes for saleWebFeb 6, 2014 · Ubiquitin-specific protease 7 (USP7) plays a dualistic role in p53 regulation and has been proposed to deubiquitylate either p53 or MDM2. Here, we show that guanosine 5'-monophosphate synthase (GMPS) is required for USP7-mediated stabilization of p53. Normally, most GMPS is sequestered in the cytoplasm, separated from nuclear … powdersville tactical supplyWebGmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP : 0.550: surA: Peptidyl-prolyl cis-trans isomerase sura; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in ... powdersville sc handymanhttp://amigo.geneontology.org/amigo/term/GO:0003922 towed bodyWebJan 1, 1996 · The crystal structure of GMP synthetase serves as a prototype for two families of metabolic enzymes. The Class I glutamine amidotransferase domain of GMP synthetase is found in related enzymes of ... towed battery chargerWebMetabolite gln__L_c in iJO1366. L-Glutamine. towed cable matlab code