WebJan 23, 2024 · Chloral hydrate is a mild hypnotic that is used to treat simple insomnia. Despite many years of use, chloral hydrate has not been implicated in causing serum enzyme elevations or clinically apparent liver … WebChloral hydrate is one of the oldest sedatives available. It is still used therapeutically; however, its use has decreased over time because of the availability of newer agents with …

Chloral hydrate - Wikipedia

Chloral hydrate is rapidly converted to an active metabolite (trichloroethanol) responsible for its sedative properties, which has a half-life at therapeutic doses of up to 66 hours in neonates, 28-40 hours in infants, 8-12 hours in children, and much longer following an overdose. 2,7. No reversal agent. See more Between 1996 and 2009, ISMP published dozens of errors about chloral hydrate used for sedation involving mostly dosing errors, oversedation, and administration of the oral liquid by the IV route. The events we published included … See more In June 2014, Nordt et al. published three cases of pediatric chloral hydrate overdoses, one a fatality, that occurred in the outpatient setting … See more Since 2010, ISMP has not received additional reports of errors involving pediatric sedation with chloral hydrate, which we assumed was due in large part to the 2012 discontinuation of the only remaining … See more In addition to the risk of respiratory depression associated with most sedatives used for pediatric sedation, chloral hydrate carries several other risks worthy of mention: Resedation after discharge. Chloral … See more Webchloral hydrate, also called chloral, the first synthetically produced sedative-hypnotic drug, commonly used in the late 19th century to treat insomnia and still occasionally used to reduce anxiety or produce sleep before surgery. Chloral hydrate acts as a depressant on the central nervous system, with sedative effects similar to those of barbiturates. Chloral … dynamic modelling meaning

Chloral hydrate drug Britannica

WebChloral hydrate has been used in human and veterinary medicine as a sedative and hypnotic drug since the mid-19 th century. Chloral hydrate's effects are primarily caused by its … WebChloral Hydrate: Safety Risks Still Worth Mentioning J Emerg Nurs. 2024 Jan;44(1):81-83. doi: 10.1016/j.jen.2024.09.002. Author Susan F ... 29306424 DOI: … Web(b) Chloral hydrate CCH OH Cl Cl Cl OH C 2 H 3 Cl O 2 Relative molecular mass: 165.40 CHLORAL AND CHLORAL HYDRATE Chloral and chloral hydrate were considered by previous IARC Working Groups in 1995 and 2004 (IARC, 1995, 2004). New data have since become available and these have been taken into consideration in the present evaluation. … dynamic model of multilingualism