2024 Itm2c cancer

Itm2c cancer

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August undefined, 2024

Web29 mrt. 2024 · ITM2C integral membrane protein 2C [ Homo sapiens (human) ] Gene ID: 81618, updated on 22-Sep-2024 Download Datasets Summary Official Symbol ITM2C … Web15 mei 2014 · The integral membrane protein 2a (Itm2a) is one of the BRICHOS domain-containing proteins and is structurally related to Itm2b and Itm2c. It is expressed preferentially in the T lineage among hematopoietic cells and is induced by MHC-mediated positive selection. However, its transcriptional regulation and function are poorly …

Single cell type - ITM2C - The Human Protein Atlas

Web15 feb. 2024 · Immunohistochemistry on tumor specimens from 170 patients showed that GRWD1 is highly expressed in NSCLC tissues and positively correlated with tumor size, … WebITM2C (Integral membrane protein 2C; also BRI3 and cerebral protein 14) is a 36‑38 kDa member of the BRI 3 family of proteins. It is found on neurons and appears to interact … blasingame burch garrard athens ga

ITM2C Gene - GeneCards ITM2C Protein ITM2C Antibody

WebThe Brain section describes gene expression in various regions of the human, mouse and pig brain, both on the mRNA and protein level. Single celli. The Single Cell Type section describes RNA expression in single cell types based on scRNAseq from human tissues. Transcriptomics analysis of human blood and cultured cell lines are also presented. Web28 jun. 2024 · The systematic integration of data from genomic characterization and genetic screening of cancer cell lines can identify gene dependencies induced by specific somatic alterations and inform the... WebThe Pathology section contains mRNA and protein expression data from 17 different forms of human cancer. Correlation analysis based on mRNA expression levels of human … blasingame burch garrard \\u0026 ashley lake oconee

An essential role of RNF187 in Notch1 mediated metastasis of ...

Knockdown of PPP5C Inhibits Growth of Hepatocellular

Web18 okt. 2014 · As known, PPP5C is a Ser/Thr phosphatase. Although several substrates of PPP5C, such as Chk1, have been reported, the mechanisms of its function in cancer … Web19 sep. 2014 · The miR-196 target gene and downstream molecular mechanisms were confirmed by RT-qPCR, western blot, luciferase reporter and confocal microscopy analyses. miR-196 expression was determined in paired cancer and adjacent normal tissues from oral cancer patients. Results frank appliance repairWebITM2C, often called transmembrane protein BRI3, is highly expressed in brain tissue. Yeast two-hybrid screen system revealed that BRI3 could interact with beta-secretase beta-amyloid protein converting enzyme (BACE)1 and the microtubule-destabilizing protein SCG10 (STMN2). It may play a role in TNF-induced cell death and neuronal differentiation. blasingame burch garrard \\u0026 ashley athens ga

"WebITM2C: Other names/aliases: BRI3 BRICD2C E25 E25C ITM3: Species: Homo sapiens: Database cross references - ITM2C: ExoCarta: ExoCarta_81618: Entrez Gene: 81618: HGNC: 6175: MIM: ... Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. Authors: Kharaziha P, Chioureas D, … " - Itm2c cancer

Itm2c cancer

Itm2a, a target gene of GATA-3, plays a minimal role in regulating …

Web15 mei 2014 · The integral membrane protein 2a (Itm2a) is one of the BRICHOS domain-containing proteins and is structurally related to Itm2b and Itm2c. It is expressed preferentially in the T lineage among hematopoietic cells and is induced by MHC … WebRNA cancer category: Cancer enhanced (glioma) PROTEIN EXPRESSION i Antibody staining in 20 different cancers is summarized by a selection of four standard cancer …

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Web18 okt. 2014 · Hepatocellular carcinoma (HCC) is well known for its prevalence, which accounts for about 90 % of primary liver cancer around the world [ 1, 2 ]. HCC is mainly caused by chronic hepatitis B, chronic hepatitis C, chronic alcoholic liver disease, aflatoxin B1 intake, non-alcoholic fatty liver disease, and other hereditary diseases [ 2 ]. WebExpression of ITM2C in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our …

WebIt has been implicated in various neurological disorders, as well as in cancer. However, its role in gastric cancer (GC) remains unknown. Thus, the present study aimed to … WebNegative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha - and beta-secretase. Binding to the beta-secretase …

Web2 sep. 2024 · Background Aberrant activation of Notch signaling has been causally linked to the metastasis of hepatocellular carcinoma (HCC), however the underlying molecular mechanisms are still poorly understood. RING finger protein 187 (RNF187) was recently revealed to be a driver of several cancers, but its expression pattern and biological … Web12 feb. 2024 · BackgroundHigh expression of integral membrane protein 2A (ITM2A) was reported to be associated with favorable prognosis in several solid tumors including breast cancer. This study aimed to investigate the role of ITM2A in breast cancer, especially in respect to tumor microenvironment.MethodsITM2A expression was evaluated based on …

WebCell. 125 (4): 801–14. مايو 2006. doi: 10.1016/j.cell.2006.03.032. PMID 16713569. "The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer". Molecular Cancer Research. 4 (11): 861–72.

WebType I membrane-bound, as well as soluble, furin has a pre-eminent role in ITM2C proteolytic processing. PCSK7 and PCSK5 may also be involved although to a lesser extent. The soluble form of PCSK7 is incapable of processing ITM2C. Fails to undergo shedding by ADAM10 and intramembrane cleavage by SPPL2B. Keywords PTM frank arce cwaWebITM2C Gene - Somatic Mutations in Cancer Gene GRCh38 · COSMIC v97 Gene view The gene view histogram is a graphical view of mutations across ITM2C. These mutations … frank archer obituaryWebExpression of ITM2C in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. frank araps attorney njWeb1 jul. 2016 · Prostate cancer (PCa) is the most prevalent malignancy in males, making it the second cause of cancer death [1], [2], [3]. Androgen receptor (AR) is largely involved in PCa development and growth [4]. Therefore, androgen deprivation therapy (ADT) with surgical castration or anti-androgen treatment is an effective treatment of PCa [4], [5]. frankard foundationWeb15 aug. 2015 · It is already known that cancer cells display high rates of glycolysis to produce their adenosine triphosphate (ATP) and some investigations suggest this is due to alterations of signaling pathways that govern glucose uptake and utilization [ 7, 8 ]. frank aragona fathom realtyWebWe projected scRNA-seq profiles of tumor-associated T cells from four different human cancers 27,51,52,53 (non-small cell lung cancer (NSCLC), colorectal cancer (CRC), breast cancer (BC), and ... blasingame burch garrard \\u0026 ashley p.cWeb12 feb. 2024 · Methods: ITM2A expression was evaluated based on qRT-PCR results on breast cancer specimens, as well as TCGA and GEO datasets. The influence of ITM2A … frank archer