WebMar 24, 2024 · Three jatrophanes, euphoscopin C (4), euphorbiapene D (6), and euphoheliosnoid A (5), showed cytotoxicity against a paclitaxel-resistant A549 human lung cancer cell line with IC 50 values of 6.9, 7.2, and 9.5 μM, respectively, but were inactive against the parent A549 human lung cancer cell line (IC 50 > 10 μM). It was found that … WebDec 7, 2024 · A549/TAX cells were paclitaxel-resistant A549 cells overexpressing CTSL and characterized by epithelial-mesenchymal transition (EMT). We showed that miRNA-200c and CTSL were reciprocally linked in ...
A549 – A model for non-small cell lung cancer - Labcorp …
WebFeb 19, 2024 · In our previous study, we demonstrated that paclitaxel nanoparticles (PTX-NPs) exhibited greater antitumor activity against A549 cells in vivo and exerted the strongest antitumor effect at 15 hours after light onset (HALO). 23 Moreover, a previous study demonstrated that cell viability at 15 HALO was the lowest among the four time points ... WebSynthesis of Novel Conjugated Linoleic Acid (CLA)-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for the Delivery of Paclitaxel with Enhanced In Vitro Anti … the spaces 5 and 4 have the same resistance
Synergistic interaction of gemcitabine and paclitaxel by modulating ...
WebApr 22, 2014 · Micro-RNA profiles of paclitaxel resistant and paclitaxel sensitive A549 cells. miRNA array profiles of paclitaxel sensitive (C1 and C2) and resistant (Tx1 and Tx2) lung cancer cell lines was shown. Supervised hierarchical clustering of cell lines based on their differential miRNAs expression with ΔLMR≥2 between the two groups was exhibited. WebPaclitaxel Inhibits A549 Cell Cycle. Regulating cell cycle distribution is an effective way to treat the proliferation of lung adenocarcinoma cells. The results demonstrated that paclitaxel significantly inhibited the expression of cell cycle proteins, CDK1,2,4,6, PCNA, Orc1-6, Mcm2-7, Kip1,2, Cyc A, Cyc B and Cyc D when compared with the ... WebMay 25, 2010 · The paclitaxel-resistant A549-Taxol cell line was established as previously reported. Briefly, the cell lines were selected to be paclitaxel resistant by continuous … the spaces apartments omaha ne