WebSpreading depression triggers ictaform activity in partially disinhibited neuronal tissues ... There is unequivocal electrophysiological evidence that spreading depression (SD) can trigger ... Web10 Aug 2024 · Spreading depolarization (SD), a phenomenon discovered during a study of the generation and spread of electrically evoked epileptiform field potentials (EFPs) in an …
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Spreading depression triggers ictaform activity in partially ...
WebExtra- and intracellular potentials were recorded from neurons and glia during spreading depression (SD) in cerebral cortex of cats. The glial membrane depolarized during SD and the time course of depolarization was concurrent with the surface DC change of SD. The glial depolarization evoked by 20-Hz repetitive cortical stimulation disappeared ... WebSpreading depression (SD) is a propagating wave of depolarization followed by depression of the neuroglial activities and can modulate extracellular dopamine concentrations in the neocortex. It has been shown that the dopaminergic system plays a role in migraine. SD has been suggested as a critical phenomenon in the pathophysiology of migraine. WebAnimal experiments showed that microemboli can trigger the aura phenomenon by inducing cortical spreading depression ... CSD increases neuronal excitability and triggers ictaform activity in neuronal tissues with partial impairment of inhibitory.9 CSD also triggers migraine headache by activating neuronal Panx1 channels which contributes to ... in the story of pauls case